Milovan Rajevack has named his first starting lineup on his second stint.
Goalkeeper Jojo Wollacott and Fatawu Issahaku are set to make their debut for the Black Stars.
Ghana are currently third in Group G after winning one game against Ethiopia and losing one to South Africa.
Zimbabwe, in comparison, are bottom of the log with just one point earned so far during their game against South Africa.
Below is the lineup:
By: Mohammed Sulemana Nazeef